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M94A2466.TXT
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1994-10-25
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Document 2466
DOCN M94A2466
TI HIV-1 risk factors among self-reported heterosexual men in Mexico City:
controlling for misclassification bias.
DT 9412
AU Fernandez Difranco G; Uribe P; Hernandez MA; Gortmaker S; Harvard School
of Public Health, Department of Epidemiology,; Boston, MA 02115.
SO Int Conf AIDS. 1994 Aug 7-12;10(1):298 (abstract no. PC0118). Unique
Identifier : AIDSLINE ICA10/94370109
AB OBJECTIVE: To identify risk factors for HIV-1 infection among
heterosexual (HE) men from Mexico City controlling for potential
misclassification of sexual orientation. METHODS: From 1990-1992, 4089
male volunteers were tested for HIV-1 by CONASIDA. Of these, 1926
self-reported as HE. Double ELISA and a confirmatory Western blot
identified 147 HIV-1 positive HE and 969 HIV-1 negative homosexuals
(HO). Risk factors for HIV-1 infection among HE men were evaluated using
a questionnaire. A multivariate misclassification scale of HE was
developed based on non-sexual behavior and socio-economic indicators.
Homosexuality was expected to be under-reported, despite the anonymity
of the questionnaire, due to the stigma associated with HO behavior in
Mexican society. RESULTS: Using a scale derived from a multiple
regression model, we found no evidence of misclassification of HE men.
The multiple R in this regression was 0.41, indicating moderate
predictability for identifying individuals who were behaviorally HO vs
HE. Older age (p = 0.0016), less education (p = 0.0001), report of a
sexual partner with AIDS (OR = 2.95, p = 0.0026) and blood transfusion
(OR = 3.78, p = 0.0001) were related to higher risk of HIV-1 infection
by HE in a multiple logistic regression, controlling for
misclassification. CONCLUSION: Significant risk factors for HIV-1 were
found in the sample of HE males from Mexico City with no evidence of
misclassification.
DE AIDS Serodiagnosis Homosexuality Human HIV Infections/*TRANSMISSION
*HIV-1 Male Mexico Risk Factors *Sex Behavior/CLASSIFICATION
MEETING ABSTRACT
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).